EGFR and non-small cell lung carcinoma: However, we found that there were more apoptotic cells, as indicated by the presence of a significant sub-G1 population, in EGFR-mutant NSCLC cell lines HCC827 and RERF-Ad-A2 (BIM wide-type), but not in HCC2279 and PC-3 cells (BIM deletion polymorphism) (Figure 5A).