SOD1 and amyotrophic lateral sclerosis: 1987) and Zn/Cu superoxide dismutase (SOD1), involved in protection against oxidative stress (Phillips et al., 1989). SOD1 is by far the most studied in the fly, due to its strong relation with oxidative stress, aging and amyotrophic lateral sclerosis (ALS) (Renton et al., 2014; Casci and Pandey, 2015).