Accordingly, administration of DNR but not ARA-C promoted a significant increase of IFN-γ (p < 0.05), IL-1β (p < 0.01), IL-2 (p < 0.001), and IL-12 (p < 0.05) in the serum of leukemia-bearing mice (Figure S6 in Supplementary Material). This evidence concerns the gene IL1B and leukemia.