Another combination, for the treatment of MSLN-expressing NSCLC uses a combination of the anti-VEGF antibody bevacizumab with the single-chain anti-MSLN mAb SS1 (dsFv) linked to the exotoxin PE-38 from Pseudomonas (258) (NCT01051934). The gene discussed is MSLN; the disease is non-small cell lung carcinoma.