CD274 and glioblastoma: In the future, multi omics analysis will be implemented in exosomes, and we will further focus on the contribution of the PD-1/PDL-1 pathway using molecular imaging and PD-1/PDL-1 knockdown/overexpression in exosomes to reveal the mechanisms of LRRC4 in GBM microenvironment immune cells modulation through exosomes.