For this purpose, we compared RNA-seq data (GSE65422) from non-transformed B cells (resting splenic B cells and germinal center B cells analyzed directly ex vivo; and B cells activated in vitro with a-CD40 and a-IgM antibodies) with B cells resembling diffuse large B cell lymphoma (DLBCL) (Zhang et al., 2015). The gene discussed is CD40; the disease is diffuse large B-cell lymphoma.