PPIB and metabolic syndrome: Serum CypB level increased gradually with increasing number of MetS components, from the subjects with none of the components (124.26 ± 47.83 ng/mL) to those with all five components (222.42 ± 114.41 ng/mL) (Figure 1C), thus confirming the internal conformance of the abovementioned findings (P trend < 0.001).