IGF1 and Laryngopharyngeal Reflux: Severe dwarfismCentral obesity↑ LDL cholesterol levels↑ Systolic blood pressure↓Cranial volume, frontal bossing↓Depth of skull,↓facial height, Laryngopharyngeal reflux Laryngeal constriction↓↓ GH and IGF-1 serum levels