FUS regulates several RNA metabolic processes, including RNA splicing, and is linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) (Robberecht and Philips, 2013; Scotti and Swanson, 2016; van Es et al., 2017). This evidence concerns the gene FUS and amyotrophic lateral sclerosis.