Evaluation of the influence of APOE ε4 status on amyloid and tau deposition in the post-stroke sub-cohort revealed a statistically significant higher amyloid load in APOE ε4 positive post-stroke subjects compared to APOE ε4 negative subjects in the subiculum and entorhinal cortex respectively (p = 0.01) (Figure 7A). The gene discussed is APOE; the disease is Stroke.