Contrary to what is expected, a greater decrease of expression was found in concentrations corresponding to normal weight (10 ng/mL) and excess weight-obesity (100 ng/mL), which could indicate that in a condition of excess weight and obesity, there is a blockage in the expression of these receptors, which leads to adiponectin not being able to carry out its protective (antiproliferative) action during the development of breast cancer. Here, ADIPOQ is linked to obesity due to melanocortin 4 receptor deficiency.