Additionally, weak correlation between the amount of MCN-NAIP and the change of ALSFRS-R score revealed at 4 months testing period (Fig. 3A; R2 = 0.1197, P = 0.29), but NAIP upregulation shown as the change of the rate of NAIP amount indicated a reliable commitment to slow ALS progression even at 4 months testing period (Fig. 3C; R2 = 0.30767, P = 0.07). Here, NAIP is linked to amyotrophic lateral sclerosis.