Interestingly, we found that these cells were enriched in the stem-like marker, aldehyde dehydrogenase 1 family member A1 (ALDH1A1) which is associated with both poor cancer prognosis and a CSC phenotype50, as well as PKC-θ and LSD1-s111p and moreover, there was increased colocalization between PKC-θ and LSD1-s111p (Fig. 5e). The gene discussed is KDM1A; the disease is cancer.