NPPB and type 2 diabetes mellitus: In the present study, treatment with liraglutide for 6 months led to a significant reduction of arterial stiffness, oxidative stress burden and NT-proBNP level in parallel with an improvement of LV longitudinal myocardial strain and strain rate, LV twisting–untwisting and endothelial function as assessed by FMD in newly diagnosed, treatment-naive T2DM patients.