Our studies in a TB endemic community in the city of Medellín, Colombia, have also provided evidence that the dosR encoded Rv1737c (NarK, nitrate reductase), Rv2029c (PFKB, phosphofructokinase B), the hypothetical protein Rv2628, and the resuscitation-promoting factors (Rpf), Rv0867c (RpfA) and Rv2389c (RpfD), induced higher production of IFNγ and a higher frequency of T-cells with a CD45RO+CD27+ (Tcm) phenotype in 7-day stimulation assays of peripheral blood mononuclear cells (PBMCs) of LTBI compared to active TB [29, 30, 33]. The gene discussed is CD27; the disease is tuberculosis.