IFNG and tuberculosis: Remarkably, in a one-year longitudinal study in Brazilian subjects recently exposed to TB, classified by IGRA and TST positivity, PBMCs stimulation with latency antigens, including Rv2029c, it was found that combining the IFNγ responders to Rv2029c, Rv2031c plus Rv2034 detected 90.3% of IGRA-RD1(+) and 66.7% of TST(+) contacts, while 95% were identified by classifying them as TST(+) IGRA-RD(+) and 11% as TST(−) IGRA(−).