In this study, we aim to investigate the association of 7 SNPs of lipid metabolism genes (LIPC rs1800588, LPL rs320, APOC3 rs5128, CETP rs5882, PON1 rs662, APOA5 rs662799, APOB rs693) with the risk of developing CAD in Chinese Han population. The gene discussed is APOA5; the disease is coronary artery disorder.