SH2B3 and coronary artery disorder: The C-allele of the missense variant, rs3184504, in SH2B3, associated with higher birth weight in our study, has been associated with multiple cardiovascular traits [lower SBP and DBP (19,20), altered lipid levels and lower risk of coronary artery disease, CAD (21,22)], altered haematological traits (23–26), lower risk of autoimmune diseases and autoimmune disorders (27–32), lower kynurenine levels (33), higher risk of tonsillectomy (34) and higher risk of colorectal and endometrial cancer (35).