PTPRQ and deafness: Next-generationtargeted sequencing of 127 deafness genes in the proband detected two novel variants, a homozygous missense variantin PTPRQ (c.2599 T>C, p.Ser867Pro and a heterozygous missense variant in MYO1A (c.2804 T>C, p.Ile935Thr),both of which were absent in unaffected sibs and two hundred unaffected controls.