It will also be illuminating to extend the analysis of Rab10 (and perhaps Rab8A/B, whose shared motif for LRRK2 phosphorylation is more challenging to probe specifically) phosphorylation in a much larger panel of control and PD brains, focusing on the substantia nigra and striatum, in addition to the cingulate cortex analysis reported here [23]. The gene discussed is RAB10; the disease is Parkinson disease.