Infection of MEFwt in the presence of nocodazole did not reveal any ICP8 (S5Gi Fig), whereas in MEF-Impα1-/- (S5Hi Fig) and MEF-Impα3-/- (S5Ii Fig), there was some nuclear ICP8, although considerably less than in MEFwt (S5Fi Fig) or MEF-Impα4-/- (S5Ji Fig). The gene discussed is BPNT2; the disease is infection.