IL10 and babesiosis: IL-10 was observed to be increased in Plasmodium falciparum-infected patients in agreement with our study [64] although we observed that IL-10 values reverted to values seen in healthy dogs within 6 days post-diagnosis both in uncomplicated and complicated cases indicating that babesiosis could disrupt the IL-10-producing regulatory B cell mechanisms and the fate of the disease would in part be determined by the initial levels of inflammatory cytokines rather that by the sustained inhibition of the immune reponse.