The cancer preventive effects, as well as other health benefits, of this micronutrient have primarily been linked to the oxidoreductase function of these selenoproteins, particularly thioredoxin reductase 1 (TR1), 15 kDa selenoprotein (Sep15) and glutathione peroxidase 2 (GPx2) [32]. The gene discussed is SELENOF; the disease is cancer.