Recently, a new identification method using whole-exome sequencing was developed, which included detection of rare homozygous missense variants (c.526C>T (p.Arg176Trp) and c.629C>T (p.Ala210Val)) in SLC45A1, encoding another cerebral glucose transporter which indicates that recessive mutation in SLC45A1 (second cerebral glucose transporter in addition to GLUT1) which cause intellectual disability and epilepsy. Here, SLC45A1 is linked to Intellectual disability.