MMP9 and uveitis: MMP-9 cleaves type IV collagen in basement membranes and allows the extravasion of leukocytes from the circulatory system into the aqueous humor during uveitis.10 Furthermore, various antioxidants and inhibitors of NF-κB that prevent expression of inflammatory cytokines have been shown to prevent uveitis and suggest the involvement of ROS in ocular inflammation.11, , , –15