This decreased expression of the FGF11 protein inhibits the differentiation of T cells toward Th1 and Th17 cells by inhibiting signal transducer and activator of transcription 1 (STAT1) and signal transducer and activator of transcription 3 (STAT3) protein phosphorylation while enhancing STAT5 protein phosphorylation to promote recruitment of Treg cells, which help tumor cells evade the immune system (Ye et al., 2014, 2016). Here, STAT3 is linked to neoplasm.