GMFB and Alzheimer disease: Brain proinflammatory protein glia maturation factor (GMF) which was discovered in our laboratory is involved in the pathogenesis of AD and MS/EAE (Lim et al., 1989; Zaheer et al., 2007, 2011a,b; Stolmeier et al., 2013; Thangavel et al., 2013, 2017).