TEAD2 and multiple acyl-CoA dehydrogenase deficiency: In this context, it is very intriguing that several inborn mutations in the gene encoding human ETF are known to cause glutaric aciduria type II (GAII), also called multiple acyl-CoA dehydrogenase deficiency (OMIM entry no. 231680), a disease characterized by severe non-ketotic hypoglycemia, metabolic acidosis, and excretion of large amounts of fatty acid and amino acid-derived metabolites (26, 27).