Although data on CD49d expression were unavailable in these studies, it is known that almost all trisomy 12 CLL cases express CD49d and that CD49d+ CLL usually has UM IGHV (Gattei et al., 2008; Zucchetto et al., 2013; Dal Bo et al., 2016). The gene discussed is ITGA4; the disease is B-cell chronic lymphocytic leukemia.