Herbal medicine probably controls the infectious disease mainly based on immunomodulatory agents stimulation (such as GSK3B, MAPK14, PPARγ) will probably help innate and adaptive immune, and regulation the inflammatory cytokines and proinflammatory mediators (like IL-6, IL-8, TNF-α, COX2) [47]. The gene discussed is CXCL8; the disease is infectious disease.