Concerning CYP3A4/5 polymorphisms in AD, 83.84% of the cases are EMs (CYP3A5*3/*3), 14.62% are IMs (CYP3A5*1/*3), and 1.54% are RMs (CYP3A5*1/*1), whereas, in the GP, EMs, IMs, and RMs represent 82.17%, 16.48%, and 1.35%, respectively [17]. The gene discussed is CYP3A4; the disease is Alzheimer disease.