PTGS1 and infection: In immunosuppressed Acanthamoeba sp.-infected mice a decrease in COX-1 detection was observed (Figure 6J–L) in comparison to immunocompetent Acanthamoeba sp.-infected mice (Figure 6G–I) and was about the same level as in control groups (Figure 6A–F), but still at 24 dpi immunoreactivity was higher than in the previous days of infection in this group (AS).