LEP and metabolic syndrome: When adjusted for confounders (including biometrics- age, height, leptin, 25OHD, osteocalcin, testosterone and social aspects-current smoking, coffee drinking, alcohol use, physical activity), higher OT (> = 0.74 pg/mL) predicted metabolic syndrome (OR: 2.06 (1.33–3.18), p<0.005)[14].