Moreover, C3 concentrations have been shown to be a useful biomarker to identify subjects with metabolic syndrome features [14, 22, 23] and that its increased concentrations, among other mediators such as CRP (C Reactive Protein) and ESR (Erythrocyte Sedimentation Rate), are strongly associated with insulin resistance [20], waist circumference, and both high fasting and postprandial triacylglycerol concentrations [17, 24]. This evidence concerns the gene CRP and Insulin resistance.