In this study, we assessed serum levels of liver enzymes (e.g. aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (Alk-P), and oxidative stress parameters in liver tissue, and we evaluated histological parameters and liver fibrosis to find the effect of different doses of TQ on LPS-induced liver fibrosis in male rats. This evidence concerns the gene GPT and Hepatic fibrosis.