PAK3 and breast cancer: By using bioinformatics tools such as gene ontology (GO) and pathway mapping tools such as Kyoto encyclopaedia of genes and genomes (KEGG), lncRNA-ARA was found to regulate multiple oncogenic signalling pathways such as purine metabolism, pyrimidine metabolism, focal adhesion, cell cycle, PPAR signaling and MAPK signaling in cells, all of which have been reported to contribute to acquisition of adriamycin resistance in breast cancer [4, 108–110].