H19 and cancer: High levels of H19 often correlate with poor prognosis for cancer patients, and with the development of chemoresistance in various cancers, including ovarian (cisplatin) [102], colorectal (methotrexate) [103], liver (doxorubicin) [104] lung (cisplatin) [105], and breast (paclitaxel) [17] (Figure 1).