Recently, lncRNAs such as lncRNA-ATB [12], GAS5 [13, 14], HOTAIR [15], CCAT2 [16], H19 [17], BCAR4 [18], UCA1 [19–21], LncRNA-ROR [22] and LncRNA-ARA [23] have been implicated in resistance to chemotherapy in breast cancer patients (Table 1 and Figure 1). The gene discussed is CCAT2; the disease is breast cancer.