Moreover, western blot analysis revealed the contribution of lncRNA-ROR in breast cancer cell invasion and the EMT process, as cell lines transfected with si-lncRNA-ROR showed an increased expression of E-cadherin (an epithelial marker) and decreased expression of Vimentin (a mesenchymal marker) [22] (Figure 2), which influenced the tamoxifen resistance ability of breast cancer cells. Here, VIM is linked to breast cancer.