CRP and neoplasm: Univariate analysis identified several variables significantly associated with RFS including T classification (HR: 7.22, 95%CI: 4.00-12.72, p<0.001), tumor size (HR:4.00, 95%CI: 2.23-7.64, p<0.001), nuclear grade (HR: 4.25, 95%CI: 2.35-7.44, p<0.001), tumor necrosis (HR: 2.79, 95%CI: 1.42-5.11, p=0.004), CRP (HR: 4.32, 95%CI: 2.50-7.55, p<0.001), the UISS (HR: 3.17, 95%CI: 1.83-5.64, p<0.001), the SSIGN (HR: 4.09, 95%CI: 2.34-7.05, p<0.001) and the COP-NLR (HR: 3.70, 95%CI: 2.10-6.46, p<0.001).