CRP and neoplasm: On multivariate analysis adjusting for those variables exhibited significant associations in univariate analysis, four variables including T classification (HR: 3.56, 95%CI: 1.46-8.71, p=0.005), tumor necrosis (HR: 2.93, 95%CI: 1.21-7.25, p=0.017), CRP (HR: 2.63, 95%CI: 1.30-5.27, p=0.008) and the COP-NLR (HR: 2.32, 95%CI: 1.22-4.36, p=0.011) still remained as significant predictors for OS.