FLT3 and acute lymphoblastic leukemia: The anti-SDF-1 effect of NOX-A12 was not limited to murine cells, as evidenced by its ability to reduce, however not abolish, SDF-1-induced migration of the human BCR-ABL-positive acute lymphoblastic leukemia (ALL) line, SUP-B15, and the human FLT3-ITD-positive line, MOLM14 (Figure 2).