For intra-pair difference in zFVC (log-ΔzFVCIP), ten sites with a p value < 10−5 were identified (Table 3), with the most significant probe identified as cg02071292 annotated to GLI (glioma) pathogenesis-related 1-like 2 (GLIPR1L2) with a p value = 7.14 × 10−8 (FDRadjp value = 0.03). This evidence concerns the gene GLIPR1L2 and central nervous system cancer.