Moreover, the Tregs specific cytokines such as Transforming growth factor β (TGF-β), Interleukin 10 (IL-10), Interleukin 17 (IL-17), Forkhead box P3 (FOXP3) concentrations were compared before and after the intervention to evaluate the possible role of Vit D in Treg function and its relation to chronic idiopathic urticaria. Here, IL17A is linked to chronic idiopathic urticaria.