Our results on the immunohistochemical NIS expression in normal thyroid and Graves’ disease (an autoimmune condition known to express high levels of NIS) (42) were in accordance to data previously reported (10, 12, 14, 17, 21), i.e., focal membrane expression of NIS in normal thyroid gland and a strong and widespread membrane NIS expression in Graves’ disease. This evidence concerns the gene SLC5A5 and Graves disease.