We also observed a statistical significant decrease (from a median of 3.8 to 0.8; P = 0.002) of the SLC5A5 expression in cases with new tumor events (Fig. 2F), lumping together 12 cases of distant metastasis (6 lung; 1 lung + bone; 1 lymph node only; 1 lung + femur + neck + pleura + liver; 1 bone; 2 unknown) and 14 locoregional recurrences (10 lymph node only; 2 left thyroid; 1 lymph node + soft tissue; 1 unknown). The gene discussed is SLC5A5; the disease is neoplasm.