IGHE and Acute bronchitis: As a traditional Chinese formula, SHL is not only used for the treatment of acute upper respiratory tract infection, acute bronchitis and light pneumonia caused by bacterium/viruses, but also applied to treat IgE-mediated allergy, such as bronchial asthma [17, 18], etc. Previous studies have showed that all of the components in SHL possess the anti-allergic activity [24–26], of which the effect of Scutellaria baicalensis on Th2 immunity has been identified [27], highly suggesting that SHL is also likely to suppress Th2 immunity.