In our previous study, we demonstrated that miR-34a decreased in HCC, and in vitro experiment has also identified that miR-34a could inhibit cell proliferation, invasion and migration, and increase caspase activity and cellular apoptosis by modulating phospho-ERK1/2 and phospho-stat5 signaling, as well as the level of c-MET [18]. The gene discussed is MET; the disease is hepatocellular carcinoma.