In contrast to the aforementioned severe neurodevelopmental disorders caused by CNV of the CNTN6 gene, deleterious point mutations (missense, nonsense, splice site, or disrupted start or stop codon) of the CNTN6 gene do not show any clinical phenotypes and have been revealed as rare mutations (approximately 1%) in a study of 942 healthy people [12]. This evidence concerns the gene CNTN6 and neurodevelopmental disorder.