Furthermore, expression analysis between dormant and fast growing phenotypes of GBM cells revealed that a specific gene set is upregulated in dormant GBMs, including e.g. ephrin type-A receptor 5 (EphA5), thrombospondin, angiomotin, insulin-like growth factor-binding protein 5 (IGFBP5), and histone cluster 1 H2B family member K (H2BK) [11, 12]. This evidence concerns the gene IGFBP5 and glioblastoma.