PTEN and hereditary clear cell renal cell carcinoma: It had been reported that PTENP1 can suppress cell proliferation and promote cell apoptosis in breast cancer [10], gastric cancer [11], oral squamous cell carcinoma [21], renal cell carcinoma [17], etc. In addition, Liu L et al. discovered that miR-193a-3p can inhibit tumor growth by directly targeting PTEN [14].