In addition, as shown in Figure 5B–5C, miR-564 expression in HCC was negatively correlated with GRB2 expression according to Spearman correlation analyses (R2 = 0.2217, P = 0.0361 in cancer tissues; R2 = 0.2017, P = 0.047 in adjacent tissues). This evidence concerns the gene GRB2 and hepatocellular carcinoma.