Based on TCGA data obtained from 180 pancreatic cancer patients, whose survival status was available, we found that patients with high miR-34a/low PLK1 expression levels had a significantly longer overall survival (OS) time (longer than 1200 days-LTS) compared to patients with low miR-34a/high PLK1 (<400 days-STS) (log-rank P < 1.92E-2) (Fig. 1a). The gene discussed is PLK1; the disease is familial pancreatic carcinoma.