CCL2 and cancer: Organoids produced by early MMTV-HER2 cancer cells displayed a reduction in secreted and peri-organoid CCL2 production upon inhibition of HER2 or NF-κB signaling with specific inhibitors38 as detected by IF analysis and ELISA (Fig. 6e–g, Supplementary Table 6 and Supplementary Fig. 5G, K, Supplementary Table 7).