Further analysis showed that CCL27 levels could also distinguish between the early stage NPC patients and the VCA-IgA–positive healthy donors, with a cut-off value of 552.71 pg/ml (AUC = 0.712, 95% CI: 0.560–0.865), a sensitivity of 59.80%, and a specificity of 84.60% (Fig 5b). This evidence concerns the gene CD79A and nasopharyngeal carcinoma.