CCL27 is a C-C motif chemokine, and the rationales to pick up CCL27 are as follows: Firstly, we have done gene chip detection between 8 NPC patients and 8 VCA-positive healthy donors, and found that CCL27 is down regulated in NPC patients; Secondly, we have tried our best to consult the reference: CCL27 is increased in inflammatory skin diseases, such as psoriasis, atopic dermatitis, and contact dermatitis, as well as other types of skin inflammation associated with T lymphocyte infiltration. Here, CCL27 is linked to inflammatory skin disease.