Recently, a study by Yoshino and co-workers reported a significant association between KIF6 rs20456 and coronary epicardial endothelial dysfunction in men only [61], while, in contrast, a previous study showed association between KIF6 rs20455 and increased risk of coronary heart disease and myocardial infarction in Han Chinese women [43]. This evidence concerns the gene KIF6 and coronary artery disorder.