APOA1 and familial hypercholesterolemia: With regards to lipidic parameters, all of them (LDL-C, HDL-C, TG, apoB and apoA1) were significantly higher in subjects with hypercholesterolemia, compared to non-hypercholesterolemic individuals (p < 0.001, for all); even though there was a relatively wide standard deviation in both groups (Table 1).